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KMID : 0384119870070010057
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Korean Journal of Clinical Pathology
1987 Volume.7 No. 1 p.57 ~ p.64
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Classification of Anemias by Mean Corpuscular Volumne(MCV) and Red Cell Volume Distribution width(RDW)
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金福伊/Kim, Bog Yi
金昌坤/李惠洙/崔三任/Kim, Chang Kon/Lee, Hye Soo/Choi, Sam Im
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Abstract
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To investigate the significance of classification of anemias by mean corpuscular volume(MCV) and red cell volume distribution width(RDW) in the complete blood count (CBC) of the peripheral blood obtained with a Coulter Counter Model S Plus Il, the authors performed this study.
Materials used in this study were 532 cases of inpatients and outpatients of Chon￢buk National University Hospital, including 1 4 cases of nonanern `group with nor￢mal hemoglobin level and 388 cases of anemic group with low hemoglobin level (less than 14 g/dl for male, and less than 12 g/dl for female). Anemic group was classified as a causing disorder, mean levels of MCV and RDW were calculated in regard to every disorder, and analyzed.
Results are as follows;
1. Nonanemic group had normal MCV and normal RDW (homogeneous normocytic), and among the anemic group, normal RDW were observed in chronic diseases such as diabetes, tuberculosis, chronic renal failure, and congestive heart failure, malignant solid tumor, infectious disease, such as salmonellosis and pneumonia, burn, posthemorrhagic state, and idiopathic thrombocytopenic purpura. Acute lymphocytic and myelocytic leukemia, chronic myelogeneous leukemia, chronic liver diseases, cardiac diaeases as valvular disorder had normal ICV and high RDW (heterogeneous normocytic),
2. Iron deficiency anemia was heterogeneous microcytic (low MCV and high RDW) and aplastic anemia was homogeneous macrocytic(high MCV and normal RDW).
3. Disorders of anemias with low MCV and normal RDW (homogeneous microcytic) and high MCV and high RDW (heterogenous macrocytic) were not included in this study.
4. MC showed similar findings as MCV, and MCHC was within norma l limits in
all diseases, so these indices didn´t have additional significance was not authorized.
In conclusion, we suggest that MCV and RDW are useful indicators for correct
classification of anemias and these are helpful for the early diagnosis and treatment of anemias.
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KEYWORD
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